The collection of cultural history presents a fund of the material of the exceptional significance for studying the courses of historical and cultural events in the area of Kruševac, but it is also the testimony of the influence of Kruševac and notable people from Kruševac through their political, military and social actions on creating the history of modern Serbian state. It was formed in 1998, and in 2011 it was separated from the ethnological and joined to the historical department. The collection contains around 3000 objects and includes postcards, correspondence cards, photographs, archival material, legacy of the academician Vladan Đorđević and objects related to the cultural-historical life of Kruševac and the surrounding. The collection is for the most part museologically elaborated. It is open and constantly grows through researches, donations and purchases, according to the criteria of its significance for documenting the accelerated cultural-historical processes in the town itself.